Mood and brain
Published human studies in mood, cognition and neurological conditions.
This page lists published studies. It reports what the authors did and found, with the limits of each study. It is not advice.
31 studies listed, newest first.
- Targeting PTSD with ultramicronized palmitoylethanolamide: Results from a randomized trial integrating pharmacotherapy and cognitive behavioral therapyRandomised controlled trialHumans
- Phase 2 study of palmitoylethanolamide combined with luteoline in frontotemporal dementia patientsRandomised controlled trialHumansWith luteolin
- Effects of palmitoylethanolamide in clinical high-risk for psychosis: A nonrandomized open-label trialOpen-label, no control groupHumans
- Palmitoylethanolamide supplementation for human health: A state-of-the-art systematic review of Randomized Controlled Trials in patient populationsReviewHumans
- The effects of formulated palmitoylethanolamide supplementation on indicators of stress and heart rate variability in female university students: a randomised cross-over trialRandomised controlled trialHumans
- Assessing the biobehavioral effects of ultramicronized-palmitoylethanolamide monotherapy in autistic adults with different severity levels: a report of two casesCase seriesHumans
- Formulated Palmitoylethanolamide Supplementation Improves Parameters of Cognitive Function and BDNF Levels in Young, Healthy Adults: A Randomised Cross-Over TrialRandomised controlled trialHumans
- Micronized/ultramicronized palmitoylethanolamide improves depression and fatigue in coronavirus disease 2019 (COVID-19) survivorsObservational studyHumans
- Questioning the role of palmitoylethanolamide in psychosis: a systematic review of clinical and preclinical evidenceReviewHumans
- What Is the Role of Palmitoylethanolamide Co-Ultramicronized with Luteolin on the Symptomatology Reported by Patients Suffering from Long COVID? A Retrospective Analysis Performed by a Group of General Practitioners in a Real-Life SettingObservational studyHumansWith luteolin
- Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndromeRandomised controlled trialHumansWith luteolin
- Efficacy and safety of palmitoylethanolamide as an adjunctive treatment for acute mania: A randomized, double-blind, placebo-controlled trialRandomised controlled trialHumans
- Synaptic Effects of Palmitoylethanolamide in Neurodegenerative DisordersReviewHumansOther animalsWith luteolin
- Therapeutic effect of palmitoylethanolamide in cognitive decline: A systematic review and preliminary meta-analysis of preclinical and clinical evidenceMeta-analysisHumansOther animals
- Effect of Ultra-Micronized Palmitoylethanolamide and Luteolin on Olfaction and Memory in Patients with Long COVID: Results of a Longitudinal StudyOpen-label, no control groupHumansWith luteolin
- Effects of Palmitoylethanolamide on Neurodegenerative Diseases: A Review from Rodents to HumansReviewHumansOther animals
- Adjuvant palmitoylethanolamide therapy with risperidone improves negative symptoms in patients with schizophrenia: A randomized, double-blinded, placebo-controlled trialRandomised controlled trialHumans
- A Phase-2 Pilot Study of a Therapeutic Combination of Delta-9-Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's SyndromeOpen-label, no control groupHumansWith delta-9-tetrahydrocannabinol (THC)
- Palmitoylethanolamide and Its Biobehavioral Correlates in Autism Spectrum Disorder: A Systematic Review of Human and Animal EvidenceReviewHumansOther animals
- An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory EventsReviewHumansOther animalsWith luteolin
- Palmitoylethanolamide: A Nutritional Approach to Keep Neuroinflammation within Physiological Boundaries. A Systematic ReviewReviewHumans
- Effects of the glial modulator palmitoylethanolamide on chronic pain intensity and brain functionOpen-label, no control groupHumans
- Role of palmitoylethanolamide (PEA) in depression: Translational evidenceReviewHumansOther animals
- Co-ultraPEALut: Role in Preclinical and Clinical Delirium ManifestationsControlled trialHumansOther animalsWith luteolin
- Short-Term Ultramicronized Palmitoylethanolamide Therapy in Patients with Myasthenia Gravis: a Pilot Study to Possible Future Implications of TreatmentOpen-label, no control groupHumans
- Palmitoylethanolamide as adjunctive therapy in major depressive disorder: A double-blind, randomized and placebo-controlled trialRandomised controlled trialHumans
- Palmitoylethanolamide as adjunctive therapy for autism: Efficacy and safety results from a randomized controlled trialRandomised controlled trialHumans
- Ultra-micronized Palmitoylethanolamide: An Efficacious Adjuvant Therapy for Parkinson's DiseaseObservational studyHumans
- Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to ManObservational studyHumansOther animalsWith luteolin
- Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple SclerosisRandomised controlled trialHumans
- Acetylcholine receptors from human muscle as pharmacological targets for ALS therapyObservational studyHumans