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Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional Viewpoint

Aniello Schiano Moriello, Vincenzo Di Marzo, Stefania Petrosino. Animals (Basel). 2022 Jan 31;12(3):348.

ReviewDogsCatsHumans

Design
Review
Subjects
Not stated in the abstract
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
How gut microbiome and endocannabinoidome tone interact in health and disease, with attention to companion animals and dietary interventions such as palmitoylethanolamide

What the authors reported

Gut dysbiosis and altered endocannabinoidome tone interact, the authors say, and this may relate to gastrointestinal and metabolic disease and neuroinflammatory disorders. They briefly discuss dietary interventions including probiotics, prebiotics and endocannabinoid-like modulators such as palmitoylethanolamide for intestinal health.

Limits of this study

A narrative review with no new data and no trial numbers. Two authors are employees of Epitech Group, which makes palmitoylethanolamide products, and two hold patents on adelmidrol or PEA.

Source

PubMed 35158670 · doi:10.3390/ani12030348

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.