Cannabinoids and Sleep: Exploring Biological Mechanisms and Therapeutic Potentials
ReviewHumans
- Design
- Review
- Subjects
- Not stated in the abstract
- Dose used in the study
- Not stated in the abstract
- Duration
- Not stated in the abstract
- What was measured
- How THC, CBD and palmitoylethanolamide affect sleep regulation and sleep disorders
What the authors reported
This review reported:
- THC can promote sleep at first but alters sleep architecture with long-term use, the authors write.
- CBD is reported to improve sleep quality without psychoactive effects.
- PEA is described as acting on the endocannabinoid system and PPAR receptors, with a favourable safety profile cited for CBD and PEA.
- They call for research on dosage, safety and efficacy in different patient groups.
Limits of this study
A narrative review with no new data, search method or trial list in the abstract. It gives no numbers on how PEA affected sleep. The authors declare no conflicts of interest.
Source
PubMed 38612415 · doi:10.3390/ijms25073603
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.