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HomeResearchArianna 2022

Investigational drugs for the treatment of olfactory dysfunction

Arianna Di Stadio, Cinzia Severini, Andrea Colizza, Marco De Vincentiis, Ignazio La Mantia. Expert Opin Investig Drugs. 2022 Sep;31(9):945-955.

ReviewHumans

Design
Review
Subjects
Not applicable; a narrative review
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
What treatments exist for olfactory dysfunction, grouped by topical versus systemic administration, using post-COVID smell loss as the model

What the authors reported

Comparing topical and systemic treatment results can suggest whether an olfactory disorder has a peripheral or central origin, the authors argue, and treatments tested in COVID-19 smell loss might also be options for neurodegenerative olfactory disease. The abstract does not name palmitoylethanolamide.

Limits of this study

A narrative review and expert opinion, not new data. PEA is not mentioned in the abstract. Funding and conflicts not stated in the abstract.

Source

PubMed 35983993 · doi:10.1080/13543784.2022.2113054

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.