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HomeResearchRosalia 2020

Management of Traumatic Brain Injury: From Present to Future

Rosalia Crupi, Marika Cordaro, Salvatore Cuzzocrea, Daniela Impellizzeri. Antioxidants (Basel). 2020;9(4):297.

ReviewHumansOther animals

Design
Review
Subjects
Not stated in the abstract
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
What's known about managing traumatic brain injury: the inflammatory cascade that drives secondary injury, animal models, and existing and potential treatments for inflammation and behavioural deficits

What the authors reported

Secondary injury after traumatic brain injury is described as an inflammatory cascade with blood-brain barrier breakdown, oedema, immune cell infiltration and cytokine release, and the authors review neuroprotective strategies against it. The abstract does not mention palmitoylethanolamide findings or give numbers.

Limits of this study

A narrative review, not a trial. Salvatore Cuzzocrea holds patents with Epitech Group, which makes ultramicronised PEA; the authors say these are unrelated to the review.

Source

PubMed 32252390 · doi:10.3390/antiox9040297

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.