The immune system and autism spectrum disorder: association and therapeutic challenges
ReviewHumans
- Design
- Review
- Subjects
- Not stated in the abstract
- Dose used in the study
- Not stated in the abstract
- Duration
- Not stated in the abstract
- What was measured
- Whether immune and autoimmune dysfunction contributes to autism spectrum disorder, and what anti-inflammatory agents, including palmitoylethanolamide, have been reported to do about it.
What the authors reported
Immune involvement in autism spectrum disorder shows up as microbiome and gut-brain axis changes, higher pro-inflammatory cytokines in patients, and more autoimmune disorders in first-degree relatives. Anti-inflammatory agents, including resveratrol and palmitoylethanolamide, have been reported to relieve manifestations of autism, though the authors say stronger studies are needed.
Limits of this study
A narrative review with no new data and no trial numbers for palmitoylethanolamide. Funding and conflicts not stated in the abstract.
Source
PubMed 34672295 · doi:10.21307/ane-2021-023
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.