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Neuro-Gastro-Cannabinology: A Novel Paradigm for Regulating Mood and Digestive Health

Fabio Turco, Viola Brugnatelli, Raquel Abalo. Med Cannabis Cannabinoids. 2023 Oct 27;6(1):130-137.

ReviewHumans

Design
Review
Subjects
Not stated in the abstract
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
A concept review linking the endocannabinoid system, gut microbiota and mood, including where palmitoylethanolamide might fit as a way to restore normal microbiota.

What the authors reported

The authors describe the endocannabinoid system's role in gut motility, permeability, secretion, immunity and visceral pain, and its two-way relationship with the microbiota and mood. They propose prebiotics or probiotics to raise endocannabinoid tone, and phytocannabinoids or endocannabinoid-like molecules such as palmitoylethanolamide to restore normal microbiota. No data are presented.

Limits of this study

A concept paper with no new data; PEA is mentioned as a proposal only. The authors have no conflicts of interest to declare.

Source

PubMed 37920559 · doi:10.1159/000534007

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.