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Food supplements based on palmitoylethanolamide plus hydroxytyrosol from olive tree or Bacopa monnieri extracts for neurological diseases

Aysha Karim Kiani, Giacinto Abele Donato Miggiano, Barbara Aquilanti, Valeria Velluti, Giuseppina Matera, Lucilla Gagliardi, Matteo Bertelli. Acta Biomed. 2020;91(13-S):e2020007.

ReviewHumansOther animalsWith hydroxytyrosol (olive extract) and Bacopa monnieri extract, discussed as supplement partners

This study tested palmitoylethanolamide together with hydroxytyrosol (olive extract) and Bacopa monnieri extract, discussed as supplement partners. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.

Design
Review
Subjects
Not stated in the abstract
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
What palmitoylethanolamide, hydroxytyrosol and Bacopa monnieri extracts offer against neuroinflammation and neurodegeneration: a review covering Parkinson disease, Alzheimer disease, spinal cord injury and stroke

What the authors reported

The three compounds share reported neuroprotective actions against shared features of neurodegenerative disease, the authors say, including protein aggregation, oxidative stress, apoptosis, excitotoxicity, calcium imbalance and inflammation. The abstract gives no numbers and no trial data.

Limits of this study

A narrative review, not a trial; it reports the authors' reading of the literature. The abstract gives no search method or study selection. The authors declare no commercial associations.

Source

PubMed 33170159 · doi:10.23750/abm.v91i13-S.10582

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.