Palmitoylethanolamide: A Nutritional Approach to Keep Neuroinflammation within Physiological Boundaries. A Systematic Review
ReviewHumans
- Design
- Review
- Subjects
- Systematic review
- Dose used in the study
- Micronised and ultramicronised forms
- Duration
- Not applicable
- What was measured
- Studies of oral micronised palmitoylethanolamide in neuroinflammatory disorders, framed around mast cells and microglia
What the authors reported
The authors argue that neuroinflammation is normally kept in check by locally made palmitoylethanolamide, and that oral micronised forms restore that control; the trials are reviewed on that basis.
Limits of this study
Both authors are Epitech employees, which the paper's conflict statement records. The review favours the company's formulations. Read alongside the independent reviews by Rankin 2020 and Gabrielsson 2016.
Source
PubMed 33333772 · doi:10.3390/ijms21249526
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.