Gut
Published human trials in gut conditions, including irritable bowel syndrome.
This page lists published studies. It reports what the authors did and found, with the limits of each study. It is not advice.
24 studies listed, newest first.
- Palmitoylethanolamide for Nickel Allergy: Plausible, Untested, and Worth ConsideringReviewHumans
- Palmitoylethanolamide supplementation for human health: A state-of-the-art systematic review of Randomized Controlled Trials in patient populationsReviewHumans
- Effect of Palmitoylethanolamide Compared to a Placebo on the Gut Microbiome and Biochemistry in an Overweight Adult Population: A Randomised, Placebo Controlled, Double-Blind StudyRandomised controlled trialHumans
- Therapeutic Potential of Palmitoylethanolamide in Gastrointestinal DisordersReviewHumans
- Efficacy of mast cell directed therapies in irritable bowel syndrome: a systematic reviewReviewHumansWith polydatin (palmitoylethanolamide-polydatin was one of the therapies reviewed)
- Palmitoylethanolamide and polydatin in pediatric irritable bowel syndrome: A multicentric randomized controlled trialRandomised controlled trialHumansWith polydatin
- Palmitoylethanolamide (PEA) for Prevention of Gastroesophageal Inflammation: Insights from In Vitro ModelsLaboratory studyHumansWith Zingiber officinale, Musa × paradisiaca, Opuntia ficus-indica and Olea europaea plant extracts
- Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected PatientsLaboratory studyHumansOther animalsWith adelmidrol (a PEA analogue) with hyaluronic acid, as a gel
- Role of PPAR-Allopregnanolone Signaling in Behavioral and Inflammatory Gut-Brain Axis CommunicationsReviewHumansOther animals
- Neuro-Gastro-Cannabinology: A Novel Paradigm for Regulating Mood and Digestive HealthReviewHumans
- Why Use Nutraceutical Strategies for the Irritable Bowel Syndrome?ReviewHumans
- Dietary supplements for intestinal inflammationReviewHumans
- The Enteric Glia and Its Modulation by the Endocannabinoid System, a New Target for Cannabinoid-Based Nutraceuticals?ReviewHumansOther animals
- Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional ViewpointReviewDogsCatsHumans
- Bioactive lipids in inflammatory bowel diseases - From pathophysiological alterations to therapeutic opportunitiesReviewHumansOther animals
- Endocannabinoid system mediates the association between gut-microbial diversity and anhedonia/amotivation in a general population cohortObservational studyHumans
- Palmitoylethanolamide Reduces Colon Cancer Cell Proliferation and Migration, Influences Tumor Cell Cycle and Exerts In Vivo Chemopreventive EffectsLaboratory studyHumansOther animals
- Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional DyspepsiaLaboratory studyHumansOther animals
- Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammationRandomised controlled trialHumans
- N-Acylphosphatidylethanolamines and N-acylethanolamines increase in saliva upon food mastication: the influence of the individual nutritional status and fat type in foodControlled trialHumans
- Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cellsLaboratory studyHumans
- Palmitoylethanolamide and Cannabidiol Prevent Inflammation-induced Hyperpermeability of the Human Gut In Vitro and In Vivo: A Randomized, Placebo-controlled, Double-blind Controlled TrialRandomised controlled trialHumans
- Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colonLaboratory studyHumans
- Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndromeRandomised controlled trialHumansWith polydatin