Metabolic health
Published human studies that measured body composition, blood lipids or other metabolic markers.
This page lists published studies. It reports what the authors did and found, with the limits of each study. It is not advice.
24 studies listed, newest first.
- Palmitoylethanolamide in Human and Animal ObesityReviewHumansDogsCats
- The Effects of a Food Supplement, Based on Co-Micronized Palmitoylethanolamide (PEA)–Rutin and Hydroxytyrosol, in Metabolic Syndrome Patients: Preliminary ResultsRandomised controlled trialHumansWith rutin and hydroxytyrosol
- Effect of Palmitoylethanolamide Compared to a Placebo on the Gut Microbiome and Biochemistry in an Overweight Adult Population: A Randomised, Placebo Controlled, Double-Blind StudyRandomised controlled trialHumans
- Endocannabinoid-related molecules predict the metabolic efficacy of GLP-1 receptor agonism in humans with obesityObservational studyHumans
- Palmitoylethanolamide in Postmenopausal Metabolic Syndrome: Current Evidence and Clinical PerspectivesReviewHumansOther animals
- Absorption, anti-inflammatory, antioxidant, and cardioprotective impacts of a novel fasting mimetic containing spermidine, nicotinamide, palmitoylethanolamide, and oleoylethanolamide: A pilot dose-escalation study in healthy young adult menRandomised controlled trialHumansWith spermidine, nicotinamide, oleoylethanolamide
- Changes in plasma endocannabinoids concentrations correlate with 18F-FDG PET/MR uptake in brown adipocytes in humansObservational studyHumans
- Human fasting modulates macrophage function and upregulates multiple bioactive metabolites that extend lifespan in Caenorhabditis elegans: a pilot clinical studyOpen-label, no control groupHumansOther animals
- Herbal Cannabis Use Is Not Associated with Changes in Levels of Endocannabinoids and Metabolic Profile Alterations among Older AdultsOpen-label, no control groupHumans
- Palmitoylethanolamide Promotes White-to-Beige Conversion and Metabolic Reprogramming of Adipocytes: Contribution of PPAR-αLaboratory studyHumansOther animals
- Serum lipid analysis and isotopic enrichment is suggestive of greater lipogenesis in young long-term cannabis users: A secondary analysis of a case-control studyObservational studyHumans
- The Expanded Endocannabinoid System Contributes to Metabolic and Body Mass Shifts in First-Episode Schizophrenia: A 5-Year Follow-Up StudyObservational studyHumans
- Sex differences in endocannabinoids during 3 years of Mediterranean diet intervention: Association with insulin resistance and weight loss in a population with metabolic syndromeObservational studyHumans
- Intrapersonal Stability of Plasma Metabolomic Profiles over 10 Years among WomenObservational studyHumans
- Altered endocannabinoid-dynamics in craniopharyngioma patients and their association with HPA-axis disturbancesObservational studyHumans
- Impact of Circulating N-Acylethanolamine Levels with Clinical and Laboratory End Points in Hemodialysis PatientsObservational studyHumans
- Roles of Endocannabinoids and Endocannabinoid-Like Molecules in Energy Homeostasis and Metabolic Regulation: A Nutritional PerspectiveReviewHumansOther animals
- Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammationRandomised controlled trialHumans
- Hair endocannabinoid concentrations in individuals with acute and weight-recovered anorexia nervosaObservational studyHumans
- Palmitoylethanolamide counteracts hepatic metabolic inflexibility modulating mitochondrial function and efficiency in diet-induced obese miceLaboratory studyHumansOther animals
- N-Acylphosphatidylethanolamines and N-acylethanolamines increase in saliva upon food mastication: the influence of the individual nutritional status and fat type in foodControlled trialHumans
- Effects of a High-Protein Diet on Cardiometabolic Health, Vascular Function, and Endocannabinoids-A PREVIEW StudyControlled trialHumans
- Biomarkers of response to alpha-lipoic acid ± palmitoiletanolamide treatment in patients with diabetes and symptoms of peripheral neuropathyObservational studyHumansWith alpha-lipoic acid (all treated patients received it; PEA was added in some)
- Effect of PEA on LPS inflammatory action in human adipocytesLaboratory studyHumans