Palmitoylethanolamide in Postmenopausal Metabolic Syndrome: Current Evidence and Clinical Perspectives
ReviewHumansOther animals
- Design
- Review
- What was measured
- Whether palmitoylethanolamide could help manage metabolic syndrome after menopause: laboratory and clinical evidence for effects on blood lipids, insulin sensitivity and inflammation.
What the authors reported
Laboratory and preliminary clinical data suggest palmitoylethanolamide affects blood lipids, insulin sensitivity and inflammation through PPAR-alpha, the authors say. Large clinical studies are needed to establish efficacy, dosing and long-term safety, and doses in the literature range from 300 to 1,200 mg a day with no clear standard.
Limits of this study
A review that rests mainly on laboratory and early clinical data. It names no completed trial in postmenopausal women. It was funded through an Italian Ministry of Health network, and the authors declared no conflicts.
Source
Entry checked against the full text at the publisher (MDPI) on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.