Respiratory and immune
Published human trials in respiratory infection, from the 1970s trials onward.
This page lists published studies. It reports what the authors did and found, with the limits of each study. It is not advice.
24 studies listed, newest first.
- Micronized/ultramicronized palmitoylethanolamide improves depression and fatigue in coronavirus disease 2019 (COVID-19) survivorsObservational studyHumans
- Infectious disease for the rhinologistReviewHumansWith luteolin (ultramicronised palmitoylethanolamide with luteolin, as discussed in the review)
- The Effect of Levagen+ (Palmitoylethanolamide) Supplementation on Symptoms of Allergic Rhinitis—A Double-Blind Placebo-Controlled TrialRandomised controlled trialHumans
- What Is the Role of Palmitoylethanolamide Co-Ultramicronized with Luteolin on the Symptomatology Reported by Patients Suffering from Long COVID? A Retrospective Analysis Performed by a Group of General Practitioners in a Real-Life SettingObservational studyHumansWith luteolin
- The Efficacy of Palmitoylethanolamide (Levagen+) on the Incidence and Symptoms of Upper Respiratory Tract Infection—A Double Blind, Randomised, Placebo-Controlled TrialRandomised controlled trialHumans
- A Combination of α-Lipoic Acid (ALA) and Palmitoylethanolamide (PEA) Blocks Endotoxin-Induced Oxidative Stress and Cytokine Storm: A Possible Intervention for COVID-19Laboratory studyHumansWith alpha-lipoic acid
- Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndromeRandomised controlled trialHumansWith luteolin
- Proteomics and metabolomics profiling reveal panels of circulating diagnostic biomarkers and molecular subtypes in stable COPDObservational studyHumans
- Effects of Ultramicronized Palmitoylethanolamide (um-PEA) in COVID-19 Early Stages: A Case–Control StudyControlled trialHumans
- Antioxidant and Anti-Inflammatory Activity of Combined Phycocyanin and Palmitoylethanolamide in Human Lung and Prostate Epithelial CellsLaboratory studyHumansWith phycocyanin
- Palmitoylethanolamide Reduces Proinflammatory Markers in Unvaccinated Adults Recently Diagnosed with COVID-19: A Randomized Controlled TrialRandomised controlled trialHumans
- Palmitoylethanolamide (PEA) Inhibits SARS-CoV-2 Entry by Interacting with S Protein and ACE-2 ReceptorLaboratory studyHumans
- Metabolomics of bronchoalveolar lavage in children with persistent wheezingObservational studyHumans
- The Use of Palmitoylethanolamide in the Treatment of Long COVID: A Real-Life Retrospective Cohort StudyObservational studyHumans
- Could Palmitoylethanolamide Be an Effective Treatment for Long-COVID-19? Hypothesis and Insights in Potential Mechanisms of Action and Clinical ApplicationsReviewHumans
- First Evidence of the Protective Effects of 2-Pentadecyl-2-Oxazoline (PEA-OXA) in In Vitro Models of Acute Lung InjuryLaboratory studyHumansWith PEA-OXA (2-pentadecyl-2-oxazoline, a PEA analogue, tested alongside ultramicronised PEA)
- Ultramicronized Palmitoylethanolamide (um-PEA): A New Possible Adjuvant Treatment in COVID-19 patientsReviewHumansOther animals
- Phytotherapics in COVID19: Why palmitoylethanolamide?ReviewHumans
- Micronized / ultramicronized palmitoylethanolamide (PEA) as natural neuroprotector against COVID-19 inflammationReviewHumans
- Sodium chromo-glycate and palmitoylethanolamide: A possible strategy to treat mast cell-induced lung inflammation in COVID-19ReviewHumansWith sodium cromoglycate (proposed partner)
- Sinerga may prevent recurrent respiratory infections in allergic childrenControlled trialHumansWith Kluyveromyces marxianus B0399, bovine colostrum and phenylalanine (the Sinerga supplement)
- Molecular Targets of Fatty Acid Ethanolamides in AsthmaReviewHumansOther animals
- Retrospective observational study to investigate Sinerga, a multifactorial nutritional product, and bacterial extracts in the prevention of recurrent respiratory infections in childrenObservational studyHumansWith bovine colostrum, phenylethylamine and a probiotic yeast
- Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common ColdReviewHumans