Retrospective observational study to investigate Sinerga, a multifactorial nutritional product, and bacterial extracts in the prevention of recurrent respiratory infections in children
Observational studyHumansWith bovine colostrum, phenylethylamine and a probiotic yeast
This study tested palmitoylethanolamide together with bovine colostrum, phenylethylamine and a probiotic yeast. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.
- Design
- Observational study
- Subjects
- 167 children aged 3 to 7 with recurrent respiratory infections, given either the supplement or bacterial extracts
- Dose used in the study
- Sinerga, a product containing palmitoylethanolamide, bovine colostrum, phenylethylamine and Kluyveromyces probiotic; doses not in the abstract
- Duration
- Retrospective review; the abstract gives the period as March 2013 to November 2012 (as printed)
- What was measured
- Frequency of respiratory infections that led to an antibiotic prescription, in 167 children aged 3 to 7 with recurrent respiratory infections.
What the authors reported
49 percent of children on the supplement had no antibiotic-treated infection, against 5 percent of those on bacterial extracts, and all supplement children had two or fewer episodes, against 51 percent of the comparison group.
Limits of this study
Retrospective, not randomised, not blinded, and the abstract gives no group sizes. A four-ingredient product, so nothing can be assigned to palmitoylethanolamide. A study in children; nothing in it bears on unsupervised use. Funding not stated.
Source
PubMed 25280039 · doi:10.1177/039463201402700318
Entry checked against the abstract on PubMed on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.