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HomeResearchKeppel 2013

Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold

Keppel Hesselink JM, de Boer T, Witkamp RF. International Journal of Inflammation, 2013; 2013:151028.

ReviewHumans

Design
Review
Subjects
6 clinical trials from the twentieth century, in nearly 4,000 people
What was measured
Whether palmitoylethanolamide is effective and safe against influenza and the common cold: a review of six early clinical trials

What the authors reported

The results support effectiveness and safety, the authors say, drawing on six earlier trials in respiratory infection. Palmitoylethanolamide has been known as a food component since 1957, and most research since Levi-Montalcini's 1993 work has instead concerned nerve pain and mast cell disorders.

Limits of this study

A narrative review of trials run decades ago, to the standards of their time. The entry was checked against the abstract only, which gives no trial details or numbers. The lead author has published widely in support of palmitoylethanolamide. For a modern trial in respiratory infection, see Rao 2023.

Source

doi:10.1155/2013/151028

Entry checked against the abstract and citation held by Crossref, the DOI registry on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.