Assay of NAAA Activity
Laboratory studyOther animals
- Design
- Laboratory study
- Subjects
- Not applicable; a laboratory methods chapter
- Dose used in the study
- Not applicable; radiolabelled palmitoylethanolamide is used as the enzyme substrate
- Duration
- Not applicable
- What was measured
- A protocol for assaying NAAA enzyme activity using [14C]palmitoylethanolamide and thin-layer chromatography, including enzyme preparation and substrate synthesis.
What the authors reported
NAAA prefers palmitoylethanolamide as a substrate at acidic pH, and NAAA inhibitors show anti-inflammatory and analgesic actions in animal models, the chapter reports. It presents an assay method rather than experimental results.
Limits of this study
A methods chapter, not a study of PEA's effects; it cannot show effect in people or animals. Funding and conflicts not stated in the abstract.
Source
PubMed 36152194 · doi:10.1007/978-1-0716-2728-0_22
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.