Joints
Published human trials that measured joint outcomes, including knee osteoarthritis and the jaw joint.
This page lists published studies. It reports what the authors did and found, with the limits of each study. It is not advice.
12 studies listed, newest first.
- Temporal effects of Palmitoylethanolamide (PEA) in modulating knee osteoarthritis symptoms: A randomized, double-blind, placebo-controlled trialRandomised controlled trialHumans
- Probiotics and palmitoylethanolamide (PEA) for osteoarthritic pain: individual effects in a multiple baseline design studyCase seriesHumansWith probiotics (Bifidobacterium animalis BB12, Lactobacillus rhamnosus LGG, Saccharomyces boulardii)
- Effective Management of Chronic Low Back Pain in the Elderly: A One-Year Cohort Study of Oxygen-Ozone Therapy Under CT Guidance Combined with Alpha Lipoic Acid, Palmitoylethanolamide, and MyrrhObservational studyHumansWith alpha-lipoic acid and myrrh, alongside CT-guided oxygen-ozone paravertebral injections
- A randomized interventional clinical trial assessing the safety and effectiveness of PeaNoc XL tablets in managing joint pain and inflammation in arthritis patientsOpen-label, no control groupHumansWith astaxanthin
- Orofacial Pain Management: An Overview of the Potential Benefits of Palmitoylethanolamide and Other Natural AgentsReviewHumans
- New Approach to Chronic Back Pain Treatment: A Case Control StudyControlled trialHumansWith alpha-lipoic acid and myrrh, with CT-guided periradicular oxygen-ozone injections
- Lipidomics of Cell Secretome Combined with the Study of Selected Bioactive Lipids in an In Vitro Model of OsteoarthritisLaboratory studyHumans
- Targeting Neuroinflammation in Osteoarthritis with Intra-Articular AdelmidrolReviewHumansOther animalsWith adelmidrol (a PEA analogue) with high molecular weight hyaluronic acid, by intra-articular injection
- Therapeutic Potential of Diacerein in Management of PainReviewHumansOther animals
- Effects of Palmitoylethanolamide (PEA) on Nociceptive, Musculoskeletal and Neuropathic Pain: Systematic Review and Meta-Analysis of Clinical EvidenceMeta-analysisHumans
- A double-blind randomized placebo controlled study assessing safety, tolerability and efficacy of palmitoylethanolamide for symptoms of knee osteoarthritisRandomised controlled trialHumans
- Palmitoylethanolamide Versus a Nonsteroidal Anti-Inflammatory Drug in the Treatment of Temporomandibular Joint Inflammatory PainRandomised controlled trialHumans