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Experience with nutraceutical supplements in the treatment of pelvic pain in gynaecology: case reports

Francisco Nohales Alfonso. Drugs Context. 2022 Jan 12:11:2021-10-8.

Case seriesHumansWith alpha-lipoic acid and myrrh (a nutraceutical supplement), within a multimodal programme that also included hormone therapy, antineuropathic drugs, injections, behavioural and physical interventions

This study tested palmitoylethanolamide together with alpha-lipoic acid and myrrh (a nutraceutical supplement), within a multimodal programme that also included hormone therapy, antineuropathic drugs, injections, behavioural and physical interventions. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.

Design
Case series
Subjects
Three women with acute gynaecological pelvic pain (endometriosis; obstetric anal sphincter injury after episiotomy; Bartholin gland cystectomy)
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
Pelvic pain and dyspareunia (Marinoff scale 2 or 3 at baseline), assessed with objective tools; use of other analgesic medicines

What the authors reported

Pelvic pain and dyspareunia were largely resolved with the multimodal approach, which included the alpha-lipoic acid, palmitoylethanolamide and myrrh supplement, and other analgesic, anti-inflammatory and antineuropathic medicines could be reduced or withdrawn, the author reports for each case.

Limits of this study

Three case reports with no control group. Each woman also received several other treatments, so the supplement's own contribution cannot be separated. The author declares no relevant conflicts of interest.

Source

PubMed 35106067 · doi:10.7573/dic.2021-10-8

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.