Effect of palmitoylethanolamide–polydatin combination on chronic pelvic pain associated with endometriosis: Preliminary observations
Case seriesHumansWith polydatin
This study tested palmitoylethanolamide together with polydatin. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.
- Design
- Case series
- Subjects
- 4 women with pain related to endometriosis
- Dose used in the study
- 400 mg of palmitoylethanolamide with 40 mg of polydatin, twice a day
- Duration
- 90 days
- What was measured
- Pain intensity on a visual analogue scale, use of pain medication and related symptoms.
What the authors reported
All four patients had less pain within a month. The mean pain score fell from 77.5 mm to 35 mm, and use of pain medication fell.
Limits of this study
Four patients and no control group. The authors themselves call the results anecdotal, and their statistical model was not significant at this sample size.
Source
doi:10.1016/j.ejogrb.2010.01.008
Entry checked against the abstract page at the publisher (ScienceDirect) on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.