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Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report

Gugliandolo E, Barbagallo A, Peritore AF, Cuzzocrea S, Crupi R. Animals, 2020; 10(9):1469.

Case seriesHorses

Design
Case series
Subjects
4 jumping horses, aged 7 to 16 years
Dose used in the study
2.5 g a day of ultramicronised palmitoylethanolamide, mixed into feed
Duration
2 to 4 months
What was measured
Lameness on the AAEP 0 to 5 scale, flexion tests, radiographs and response to diagnostic anaesthesia.

What the authors reported

Lameness resolved in all four horses, the authors reported, and the horses returned to showjumping competition without recurrence during the report period.

Limits of this study

Four horses and no control group. Lameness can change with rest and time, and the report cannot separate those effects from the supplement. Assessors were not blinded. The FEI lists palmitoylethanolamide as a Controlled Medication, which matters for any horse that competes. See Status and Rules.

Source

doi:10.3390/ani10091469

Entry checked against the full text at the publisher (MDPI) on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.