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Palmitoylethanolamide, an endogenous fatty acid amide, and its pleiotropic health benefits: A narrative review

Debasis Basu. J Biomed Res. 2024 Oct 22;39(3):215-228.

ReviewHumansOther animals

Design
Review
Subjects
Not applicable; this is a narrative review, not a single study
Dose used in the study
Not applicable; this is a narrative review, not a single study
Duration
Not applicable; this is a narrative review, not a single study
What was measured
What health benefits does palmitoylethanolamide have across body systems: a narrative review of its actions in neurological, psychiatric, ophthalmic, metabolic, oncological, renal, hepatic, immunological, rheumatological and gastrointestinal conditions, without new data of its own.

What the authors reported

Palmitoylethanolamide is described as having anti-inflammatory, antimicrobial, immunostimulatory, neuroprotective and pain-reducing actions, with high tolerability and safety reported in the animal and human studies cited. The review says it is used to support health across a wide range of physiological and pathological conditions.

Limits of this study

A narrative review summarising other studies, not new data of its own; it does not independently verify the claims it summarises. The authors reported no conflict of interests.

Source

PubMed 39433509 · doi:10.7555/JBR.38.20240053

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.