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Palmitoylethanolamide (PEA) in the treatment of neuropathic pain: a case study

Despina Kamper. Nutr Health. 2022 Jun;28(2):265-269.

Case seriesHumans

Design
Case series
Subjects
One 67-year-old man with post-herpetic neuralgia of 3 years' duration after shingles
Dose used in the study
Palmitoylethanolamide 900 mg daily (10 mg/kg)
Duration
Pain relief reported within 48 hours; total duration not stated
What was measured
Pain relief in a single patient; earlier studies on PEA and neuropathy were reviewed to discuss possible mechanisms.

What the authors reported

Pain relief was effective within 48 hours of starting palmitoylethanolamide at 900 mg per day, the author reports.

Limits of this study

A single case report with no control, no blinding and no stated outcome scale; it cannot show that PEA caused the improvement or that it applies to others. Funding and conflicts not stated in the abstract.

Source

PubMed 34289728 · doi:10.1177/02601060211019669

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.