Palmitoylethanolamide in the Treatment of Chronic Pain Caused by Different Etiopathogenesis
Observational studyHumans
- Design
- Observational study
- Subjects
- 610 patients with chronic pain of mixed causes not controlled by standard therapy
- Dose used in the study
- PEA 600 mg twice daily for 3 weeks, then 600 mg once daily for 4 weeks, with or without existing analgesics
- Duration
- 7 weeks
- What was measured
- Mean pain score on a numeric rating scale; adverse events.
What the authors reported
Mean pain intensity fell in patients who completed the study, regardless of the underlying condition and also in those taking no other analgesic. No adverse effects reported.
Limits of this study
Observational, no control group, no blinding. Results reported for completers only. Abstract gives no effect size or dropout count.
Source
PubMed 22845893 · doi:10.1111/j.1526-4637.2012.01432.x
Entry checked against the abstract, supplied by Devlin. Effect size and dropouts not in the abstract on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.