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Cannabinoids for the Treatment of Dermatologic Conditions

Torunn E Sivesind, Jalal Maghfour, Hope Rietcheck, Kevin Kamel, Ali S Malik, Robert P Dellavalle. JID Innov. 2022 Jan 13;2(2):100095.

ReviewHumans

Design
Review
Subjects
26 human studies (13 on systemic and 14 on topical cannabinoids) from 248 screened
Dose used in the study
Not stated in the abstract
Duration
Literature from 1965 to October 2020
What was measured
Which cannabinoids help dermatologic conditions, based on published human studies

What the authors reported

Selective CB2 agonists were reported effective in diffuse cutaneous systemic sclerosis and dermatomyositis; dronabinol for trichotillomania; sublingual CBD and THC for pain in epidermolysis bullosa. Cannabinoids may be effective for inflammatory skin disorders, the authors say, though more research is needed on dosing, safety and long-term use.

Limits of this study

A literature review; the abstract does not name palmitoylethanolamide or give PEA-specific results. Animal studies were excluded. Funding and conflicts not stated in the abstract.

Source

PubMed 35199092 · doi:10.1016/j.xjidi.2022.100095

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.