Palmitoylethanolamide Effects on Intraocular Pressure After Nd:YAG Laser Iridotomy: An Experimental Clinical Study
Controlled trialHumans
- Design
- Controlled trial
- Subjects
- 15 patients having laser iridotomy in both eyes to prevent angle-closure glaucoma
- Dose used in the study
- 2 tablets a day of PEA or placebo for 15 days before the procedure; tablet strength not given in the abstract
- Duration
- 15 days pretreatment; pressure measured at 15, 30 and 120 minutes after iridotomy
- What was measured
- Intraocular pressure before pretreatment, after pretreatment, and at three time points after Nd:YAG laser iridotomy
What the authors reported
Pressure rose significantly after iridotomy in placebo-pretreated eyes (p ≤ 0.05) but not in PEA-pretreated eyes, and the slopes of the two pressure trends differed (p = 0.022).
Limits of this study
15 patients. The abstract does not say how eyes or patients were allocated to PEA or placebo, or whether the study was blinded. Short observation (2 hours after the procedure). Tablet dose not stated.
Source
PubMed 21830938 · doi:10.1089/jop.2010.0191
Entry checked against the abstract, supplied by Devlin. Allocation method and dose not in the abstract on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.