palmitoylethanolamide.com.au
Home › Research › Keppel 2015

Palmitoylethanolamide, a Natural Retinoprotectant: Its Putative Relevance for the Treatment of Glaucoma and Diabetic Retinopathy

Keppel Hesselink JM, Costagliola C, Fakhry J, Kopsky DJ. J Ophthalmol. 2015;2015:430596.

ReviewHumans

Design
Review
Subjects
Narrative review
Dose used in the study
Up to 1.8 g a day in the trials cited
Duration
Not applicable
What was measured
The case for palmitoylethanolamide in glaucoma, diabetic retinopathy and uveitis, drawing on the eye trials and the wider trial record

What the authors reported

Palmitoylethanolamide has been tested in at least nine double-blind placebo-controlled studies since the 1970s, two in glaucoma, and found safe and effective up to 1.8 g a day, the authors state. They name commercial products, including ones notified in Italy.

Limits of this study

A narrative review whose abstract names commercial products. It does not give trial sizes, results or quality ratings, and funding and conflicts are not stated in the abstract.

Source

PubMed 26664738 · doi:10.1155/2015/430596

Entry checked against the abstract on PubMed on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.