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Effect of Palmitoylethanolamide on Visual Field Damage Progression in Normal Tension Glaucoma Patients: Results of an Open-Label Six-Month Follow-Up

Costagliola C, Romano MR, dell'Omo R, Russo A, Mastropasqua R, Semeraro F. Journal of Medicinal Food, 2014; 17(9):949-954.

Controlled trialHumans

Design
Controlled trial
Subjects
32 patients with normal tension glaucoma, randomised to palmitoylethanolamide or no treatment
Dose used in the study
300 mg of ultramicronised palmitoylethanolamide twice a day
Duration
6 months
What was measured
Eye pressure, visual acuity and visual field indices

What the authors reported

Eye pressure fell from 14.4 to 11.1 mmHg in the treated group (p < 0.01), and two visual field indices improved compared with baseline. Visual acuity did not change in either group. No side effects were recorded.

Limits of this study

Open-label, with no placebo. The comparison group received nothing, so patients and examiners knew who was treated. 32 patients and 6 months. The entry was checked against the abstract only. Funding was not listed.

Source

doi:10.1089/jmf.2013.0165

Entry checked against the abstract and citation held by Crossref, the DOI registry on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.