Clinical Study: Palmitoylethanolamide – Relief Shingles (Herpes Zoster) Pain Reduced by Average 60.9%

Research on the Pain of Shingles… 

For information purposes only.

In this study, PEA was effective and safe in the management of chronic pain in different pathological conditions. https://academic.oup.com/painmedicine/article/13/9/1121/1864240/ 

Abstract

Objective. To assess the efficacy and safety of palmitoylethanolamide (PEA), an endogenous fatty acid amide belonging to the N-acylethanolamines family, in reducing pain severity in patients with pain associated to different pathological conditions.Methods. This was an observational study conducted on 610 patients who were unable to effectively control chronic pain with standard therapies. PEA (600 mg) was administered twice daily for 3 weeks followed by single daily dosing for 4 weeks, in addition to standard analgesic therapies or as single therapy. The primary outcome measure was the mean score pain severity evaluated by the numeric rating scale. Safety was also evaluated.

Results. PEA treatment significantly decreased the mean score pain intensity evaluated in all patients who completed the study. The PEA effect was independent of the pain associated pathological condition. PEA-induced decrease of pain intensity was present also in patients without concomitant analgesic therapy. Importantly, PEA showed no adverse effects.

Conclusions. In this study, PEA was effective and safe in the management of chronic pain in different pathological conditions.

Results Summary:

“PEA treatment significantly decreased the mean score pain intensity evaluated in all patients who completed the study. The PEA effect was independent of the pain associated pathological condition. PEA-induced decrease of pain intensity was present also in patients without concomitant analgesic therapy. Importantly, PEA showed no adverse effects.”

In the graph below, the black column is the pain intensity score BEFORE supplementing with palmitoylethanolamide (PEA), the white column is the pain intensity score AFTER.  (HZ = Herpes Zoster, OA=Osteoarthrosis, DN=Diabetic Neuropathy, FBSS=Failed Back Surgery Syndrome)

The average reduction in pain across all of the conditions in the chart above was from 6.4 to 2.5 on the pain scale.   This is a 60.1% improvement in pain level.

Read the full study in Pain Medicine Journal here:  https://academic.oup.com/painmedicine/article/13/9/1121/1864240

 

Note:  Shingles is the common name for Herpes Zoster.

 

DISCLAIMER:

The information provided on this page is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you have read here raises questions or concerns regarding your health.

No claims are made here about benefits of PEA supplement in any medical condition, as PEA (not a prescription item) is governed by TGA in Australia.  Research is shown for readers education only.